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Some common painkillers may boost the odds of a heart problem. Use them wisely to lessen your risk.
In 2004, the drug maker Merck pulled rofecoxib off the market, following revelations that the popular prescription painkiller increased the risk of heart attacks and strokes. That action triggered a closer look at drugs in the same class, known as nonsteroidal anti-inflammatory drugs . These drugs, which are widely used to ease pain, quell inflammation, and cool fevers, include over-the-counter drugs such as aspirin, ibuprofen , naproxen and the prescription drug celecoxib .
Soon, all NSAIDs except aspirin were suspected of increasing heart attack risk. That prompted the FDA to mandate a warning about this side effect on all NSAID labels. Earlier this year, the agency considered dialing back the caution on naproxen, based on an analysis that showed a lower risk from naproxen compared with other NSAIDs. But a panel of expert advisers voted against the label change, so the warning remains the same for all NSAIDs.
With the exception of aspirin, all NSAIDs may boost the risk of having a heart attack.
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Nonprescription naproxen comes as tablet and a gelatin coated tablet to take by mouth. It is usually taken with a full glass of water every 8 to 12 hours as needed. Nonprescription naproxen may be taken with food or milk to prevent nausea.
Follow the directions on the package or prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take naproxen exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor or written on the package.
Shake the liquid well before each use to mix the medication evenly. Use the measuring cup provided to measure each dose of the liquid.
Swallow the delayed-release tablets and extended release tablets whole do not split, chew, or crush them.
If you are taking naproxen to relieve the symptoms of arthritis, your symptoms may begin to improve within 1 week. It may take 2 weeks or longer for you to feel the full benefit of the medication.
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