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Does Vyvanse Raise Blood Pressure

Safety And Tolerability In Short

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Randomized, Parallel-Group, Double-Blind Trials in Patients with Attention-Deficit/Hyperactivity Disorder

The efficacy and safety of LDX in the treatment of ADHD were evaluated in six randomized, parallel-group, double-blind, phase III trials . Three trials , were forced-dose titration studies in which patients were randomized to receive once-daily LDX 30, 50, or 70 mg, or placebo for 4 weeks . In these trials, dose increases followed a predefined schedule: patients randomized to LDX 30 mg received this dose throughout the study patients randomized to LDX 50 mg received 30 mg/day during week 1 and 50 mg/day during weeks 24 patients randomized to LDX 70 mg received 30 mg/day during week 1, 50 mg/day during week 2, and 70 mg/day during weeks 34. The remaining three trials utilized dose-optimization protocols: study 403 was placebo controlled, study 325 was placebo and active controlled, and study 317 was a head-to-head comparison of LDX and ATX. In these studies, patients randomized to LDX were individually optimized to LDX 30, 50, or 70 mg/day during weeks 14 based on efficacy and tolerability . Patients randomized to the reference treatment OROS-MPH in study 325 were individually optimized to 18, 36, or 54 mg/day . Patients randomized to the control treatment ATX in study 317 were optimized to 0.51.2 mg/kg if under 70 kg in weight, or 40, 80, or 100 mg/day in patients weighing 70 kg or over .

Vyvanse And Foods Or Beverages

Vyvanse can interact with certain food and beverages that contain caffeine.

Vyvanse and caffeine

Consuming caffeine in foods and drinks might add to the stimulant effects of Vyvanse. This can increase the risk of stimulant-related side effects such as anxiety, fast heartbeat, insomnia , feeling jittery, and others.

While taking Vyvanse, you should avoid consuming large amounts of foods or drinks that contain caffeine. Caffeine is found in foods such as chocolate. Its also found in drinks such as coffee, certain teas, and sodas.

You may want to try decaffeinated versions of these drinks. However, if you feel you need some caffeine, talk with your doctor. They can tell you how much is safe to have while taking Vyvanse.

Does Vyvanse Cause Different Side Effects In Females Vs Males What About In Children

No, the side effects of Vyvanse arent known to be different for females and males.*

The only side effects of Vyvanse specific to females are related to using Vyvanse during pregnancy or while breastfeeding. It may not be safe to use Vyvanse when pregnant or while breastfeeding. To learn more about this, see the What should be considered before taking Vyvanse? section below.

Vyvanse is used to treat ADHD in children ages 6 years and older. Most side effects of Vyvanse are expected to be the same in children as in adults.

Certain side effects of Vyvanse may be more common in children. These include:

  • effects on personality, such as emotional breakdown
  • slowed growth

If you have questions about your or your childs risk for certain side effects from Vyvanse, talk with your doctor.

* In this article, we use the terms male and female to refer to someones sex assigned at birth. For information about the difference between sex and gender, see this article.

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What Does Vyvanse Cost

Costs of prescription drugs can vary depending on many factors. These factors include what your insurance plan covers and which pharmacy you use. To find current prices for Vyvanse capsules in your area, visit GoodRx.com.

If you have questions about how to pay for your prescription, talk with your doctor or pharmacist. You can also visit the Vyvanse manufacturers website to see if it has support options.

Dont take more Vyvanse than your doctor prescribes. Using more than this can lead to serious side effects.

Misuse And Dependence Risk

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boxed warning for the risk of misuse and dependence. A boxed warning is the most serious warning from the Food and Drug Administration . It alerts doctors and patients about drug effects that may be dangerous.

Treatment with Vyvanse may lead to physical dependence or misuse. With dependence, your body needs a drug to feel normal. Misuse, on the other hand, means taking a drug in a way other than how your doctor prescribes. This includes taking a medication for non-medical purposes.

Misuse can lead to addiction. Some people may also develop addiction when taking Vyvanse as prescribed. With addiction, its difficult to stop taking a drug even though it may be causing harm.

Symptoms of Vyvanse misuse can include:

  • aggressive or hostile behavior
  • thoughts of harming yourself or others

What might help

Before prescribing Vyvanse, your doctor will review your medical history. Theyll look for any risk factors for misuse or dependence. Theyll also monitor you for any symptoms of misuse or dependence during your treatment.

Because Vyvanse can cause dependence, its important that you dont stop taking the drug unless your doctor tells you to. If you need to stop your treatment, your doctor will lower your dose over time. This can help prevent withdrawal symptoms .

If you have questions about stopping your Vyvanse treatment or about your risk for misuse or dependence, talk with your doctor or pharmacist.

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Are There Dangerous Drug Interactions With Vyvanse

There are many important drug interactions with Vyvanse, some of which can be serious or fatal. You can review these interactions here.

Keep a list of the medicines you take and show them to your doctor and pharmacist before you start a new medicine. This includes over-the-counter medicines, vitamins, herbs or other dietary supplements. Do not start any new medicine while taking Vyvanse without talking to your doctor first.

Your doctor or pharmacist should check to see if you are taking any drugs that can interact with Vyvanse when you start treatment, and they should also review for drug interactions each time you start a medicine.

One important interaction is between Vyvanse and a class of drugs known as MAO inhibitors. Do not use Vyvanse if you have taken an MAO inhibitor in the past 14 days due to the chance for a dangerous, possibly fatal drug interaction.

  • MAO inhibitors, or drugs with these properties, include medicines such as isocarboxazid, linezolid, methylene blue injection, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine, and others.
  • Combining MAOIs with Vyvanse can lead to dangerous high blood pressure that can be deadly.

CYP enzymes are a family of enzymes in our bodies that are primarily found in the liver and intestines. CYP enzymes have many roles, including helping to clear drugs and toxins from the body.

How Long Does Vyvanse Last In Your System

It typically takes about 2 to 3 days before Vyvanse is fully cleared from your system. However, this may vary depending on your age, weight, genetics, kidney function, or other medications you may be taking.

The effects of Vyvanse typically last for about 10 to 12 hours after you take a dose. After the effects of Vyvanse have worn off, the levels of Vyvanse in your body continue to decrease.

Vyvanse has a half-life of about 12 hours. A drugs half-life is the amount of time it takes for your body to remove half a dose of medication from your system. After you take a dose of Vyvanse, it takes about 12 hours for the amount of active drug in your body to decrease by half.

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Prolonged Vyvanse Use And The Brain

Prescription stimulants and amphetamine compounds have been approved by the U.S. Food and Drug Administration to treat attention-deficit hyperactivity disorder, and are classified as Schedule II substances because of their high potential for abuse and dependence. Stimulants are designed to increase concentration and energy levels while decreasing the need for sleep and suppressing the appetite.

Vyvanse does this by increasing the activity of several neurotransmitters, such as serotonin, norepinephrine, and dopamine. The changes in dopamine activity trigger the brains reward center and the ability to feel pleasure without the chemical support of the drug.

Those who become dependent on Vyvanse can experience feelings of depression, have trouble falling asleep or staying asleep, or notice a distinct lack of motivation as a result of running out of Vyvanse. Abusing Vyvanse can increase suicidal thoughts or aggressive behavior, and someone who is abusing the drug for extended periods will experience the emotional toll it takes during withdrawal.

Natural dopamine production will be inhibited, which causes low moods and the inability to experience pleasure without the drug. The longer Vyvanse is used, the more intense the mood swings will become when it is absent from the body. These problems can be fixed over time with long-term abstinence.

Vyvanse And The Circulatory And Respiratory Systems

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One of the more common cardiovascular system side effects is a slightly faster heart rate. You may also have a substantial elevation in heart rate or blood pressure, but this is less common. It can also cause cardiac arrhythmias.

Vyvanse can also cause problems with circulation. You may have circulation problems if your fingers and toes feel cold or numb, or if your skin turns blue or red. If that happens, tell your doctor.

Rarely, Vyvanse can cause shortness of breath.

Vyvanse can affect your digestive system. Some of the more common digestive system problems include:

  • dry mouth

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Side Effects Of Vyvanse In Females Vs Males

Side effects of Vyvanse are usually the same in both females* and males.* There arent any side effects that are known to occur only in either sex.

Vyvanse can have harmful effects if taken during pregnancy, however. For more information, see the Precautions for Vyvanse section below.

Your doctor can answer any questions you have about your risk for side effects from Vyvanse.

* Sex and gender exist on spectrums. Use of the terms female and male in this article refers to sex assigned at birth.

List Of Lisdexamfetamine Side Effects

Stimulants like lisdexamfetamine can produce an overabundance of dopamine, flooding the brain with a sensation of pleasure. Despite any severe side effects of Vyvanse that you can experience as a result of misuse, a build-up of physical tolerance to it will make it more difficult to quit using. When a person develops a tolerance to a drug, they have to use more of it to experience the same side effects. Over time, this becomes physical dependence and eventually addiction.

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What Other Drugs Could Interact With This Medication

There may be an interaction between lisdexamfetamine and any of the following:

  • abiraterone
  • angiotensin converting enzyme inhibitors
  • angiotensin receptor blockers
  • antacids
  • antihistamines
  • antipsychotics
  • ascorbic acid
  • beta-2 agonists
  • bromocriptine
  • calcium channel blockers
  • cannabis
  • dextroamphetamine
  • diuretics
  • dorzolamide
  • ergot alkaloids
  • ethosuximide
  • monoamine oxidase inhibitors
  • multivitamins
  • narcotic pain relievers
  • nilotinib
  • serotonin/norepinephrine reuptake inhibitors
  • selective serotonin reuptake inhibitors
  • sodium bicarbonate
  • theophyllines
  • ticlopidine

Impact On Growth In Children

Does Vyvanse Cause Lasting Brain Damage?

Reductions in weight and expected height gains have been reported in multiple clinical trials assessing the use of stimulants for treatments of ADHD in children.

A 2016 controlled cohort study of children aged 6 to 12 found a delay in height growth related to the dose of stimulant medication but found no significant delay in bone age after three years of treatment. It was concluded that this lack of correlation between growth and bone age might negatively affect a childs growth potential.

A 2017 follow-up of a long-term observational study of children with ADHD assessed the group in early adulthood. It looked at the effects of long-term treatment with stimulant medications.

It showed that extended use of medications consistently from childhood to adulthood was associated with greater suppression of adult height but without a relative reduction in the severity of symptoms in adulthood.

Children should be carefully monitored by their healthcare provider while they are taking Vyvanse. Their healthcare provider may stop treatment if a problem is found.

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How Does Vyvanse Compare With Focalin And Dexedrine

Vyvanse, Focalin, and Dexedrine are prescription medications used to treat ADHD in adults and children ages 6 years and older. Theyre each a type of stimulant drug called an amphetamine.

Focalin comes in two forms:

  • immediate-release tablets called Focalin
  • extended-release capsules called Focalin XR

Dexedrine comes as sustained-release capsules.

To learn more about how Vyvanse, Focalin, and Dexedrine are alike and different, talk with your doctor or pharmacist.

Vyvanse and Adderall arent typically used together. But both drugs can be used alone to treat attention deficit hyperactivity disorder .

Adderall comes in two forms:

  • immediate-release tablets called Adderall
  • extended-release capsules called Adderall XR

If youd like to know about using Vyvanse or Adderall for your condition, talk with your doctor. Also, check out this detailed comparison for more information about these medications.

When considering Vyvanse treatment, its important to talk with your doctor. Tell them about other medical conditions you may have. Also tell them about all other medications youre taking.

These considerations are described in more detail below.

How Does This Medication Work What Will It Do For Me

Lisdexamfetamine belongs to the class of medications known as centralnervous system stimulants. It is used to treat attention deficit hyperactivity disorder . It works by affecting the balance of natural chemicals in the brain. It helps to increase attention and decrease hyperactivity and impulsiveness in children with ADHD. Lisdexamfetamine should be part of a treatment plan that includes other treatments .

Lisdexamfetamine is also used to treat moderate-to-severe binge eating disorder in adults.

Your child’s doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your child’s doctor, or are not sure why your child is taking this medication, speak to their doctor. Your child should not stop taking this medication without consulting their doctor.

Do not give this medication to anyone else, even if they have the same symptoms as your child. It can be harmful for people to take this medication if their doctor has not prescribed it.

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More Common Side Effects Of Vyvanse

Vyvanse can cause certain side effects, some of which are more common than others. These side effects may be temporary, lasting a few days or weeks. But if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist.

These are just a few of the more common side effects reported by people who took Vyvanse in clinical studies. These side effects can vary depending on which condition the drug is being used to treat.

More common side effects in people taking Vyvanse for attention deficit hyperactivity disorder include:

  • loss of appetite or decreased appetite

These side effects may be temporary, lasting a few days or weeks. But if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist.

Note: After the Food and Drug Administration approves a drug, it tracks side effects of the medication. If you develop a side effect while taking Vyvanse and want to tell the FDA about it, visit MedWatch.

* For more information about this side effect, see Side effect specifics below.

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Treatment To Help Reduce The Dangers Of Amphetamines

In these cases, in order to prevent the serious physical and psychological health consequences of prolonged stimulant use, such as an accelerated aging process in the heart or overdose, comprehensive amphetamine addiction treatment that addresses the underlying causes of addiction are necessary. Too often, patients who experience addiction to their prescriptions do not get help in facilities that also address their original diagnosis that may be a cause of amphetamine use in the first place.

At Wellness Retreat Recovery, our amphetamine addiction treatment program is evidence-based. We treat not only the addiction but the underlying causes of addiction. And, co-occurring mental and physical ailments our clients may be suffering with. We also specialize in treatment for patients who suffer from addiction to stimulants. If you need help for amphetamine addiction, you dont have to sacrifice quality medical and psychiatric care for sobriety. Call Wellness Retreat Recovery today at 888-738-0692 for information on admissions and for help.

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