What Other Drugs Will Affect Clonidine
Using clonidine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
Tell your doctor about all your other medicines, especially:
- other heart or blood pressure medications
- an antidepressant or
- any other medicine that contains clonidine.
This list is not complete. Other drugs may interact with clonidine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Avoid Medicines And Supplements That Cause Drowsiness
If combining alcohol with clonidine is a problem, so are prescription drugs, over-the-counter medications, and supplements that are also depressants. These include drugs like sleeping pills and strong pain medications, but they also include popular over-the-counter drugs and supplements like antihistamines, melatonin, and cold and flu medications.
What Drugs And Food Should I Avoid While Taking Clonidine
Avoid drinking alcohol. It may increase certain side effects of clonidine.
Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.
Avoid becoming overheated or dehydrated during exercise and in hot weather.
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What Should I Watch For While Using This Medication
Visit your care team for regular checks on your progress. Check your heart rate and blood pressure regularly while you are taking this medication. Ask your care team what your heart rate should be and when you should contact them.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medication affects you. To avoid dizzy or fainting spells, do not stand or sit up quickly, especially if you are an older person. Alcohol can make you more drowsy and dizzy. Avoid alcoholic drinks.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water will help.
Do not treat yourself for coughs, colds, or pain while you are taking this medication without asking your care team for advice. Some ingredients may increase your blood pressure.
If you are going to have surgery tell your care team that you are taking this medication.
Description Of The Intervention
Clonidine was administered as tablets in three dosages: 0.1 mg, 0.2 mg and 0.3 mg for the treatment of high blood pressure. Currently it is prescribed in the treatment of dysmenorrhoea, hypertensive crisis, Tourette’s syndrome, menopausal hot flashes, attention deficit hyperactivity disorder and as an aid in smoking cessation therapy, alcohol and opiate withdrawal. It can also be used to help in the diagnosis of pheochromocytoma.
Refer to Table 1 for recommended doses of clonidine for various indications.
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What Are The Long
As a blood pressure or ADHD medication, clonidine is intended for long-term use. There are no side effects due to long-term use other than possible hair loss or weight gain, both of which are rare and may not be due to the drug. Many side effects will improve as the body adapts to the drug. Most will fade when the drug is stopped.
Why Is This Medication Prescribed
Clonidine tablets are used alone or in combination with other medications to treat high blood pressure. Clonidine extended-release tablets are used alone or in combination with other medications as part of a treatment program to control symptoms of attention deficit hyperactivity disorder in children. Clonidine is in a class of medications called centrally acting alpha-agonist hypotensive agents. Clonidine treats high blood pressure by decreasing your heart rate and relaxing the blood vessels so that blood can flow more easily through the body. Clonidine extended-release tablets may treat ADHD by affecting the part of the brain that controls attention and impulsivity.
High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.
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More Common Side Effects
Mild side effects may go away within a few days or a couple of weeks. Talk to your doctor or pharmacist if theyre more severe or dont go away. The more common side effects that can occur with clonidine include:
- dry mouth and dry eyes
- slowed breathing or trouble breathing
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
Dosage For Attention Deficit Hyperactivity Disorder
Adult dosage
A safe and effective dose hasnt been established for adults.
Child dosage
- The starting dose is 0.1 mg taken at bedtime.
- Doses may be increased by an additional 0.1 mg per day every week until your symptoms are better or you get to the daily maximum.
- Total daily doses are 0.10.4 mg per day.
- The total daily dose is divided into 2 doses taken twice per day.
- If youre stopping clonidine, the total daily dose should be decreased by 0.1 mg every 37 days.
Child dosage
A safe and effective dose hasnt been established for this age group.
Special dosage considerations
If you have kidney disease: If you have kidney disease, your starting dosage may be lower. Your dosage may be increased based on your blood pressure.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.
Clonidine is a long-term medication. It comes with serious risks if you dont take it as prescribed.
If you dont take it at all or not on schedule
Your signs and symptoms of ADHD may get worse.
If you stop suddenly
Its important not to abruptly stop taking this drug. This can lead to a withdrawal reaction. Side effects may include:
- rapid increase in blood pressure
What to do if you miss a dose
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How Should This Medicine Be Used
Clonidine comes as a tablet and an extended-release tablet to take by mouth. The tablet is usually taken two times a day at evenly spaced intervals. The extended-release tablet is usually taken once or twice a day with or without food. Take clonidine at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take clonidine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Swallow the extended-release tablets whole do not split, chew or crush them.
Your doctor may start you on a low dose of clonidine and gradually increase your dose, not more than once every week.
Clonidine may help to control your condition but will not cure it. Continue to take clonidine even if you feel well. Do not stop taking clonidine without talking to your doctor. If you suddenly stop taking clonidine, it can cause a rapid rise in your blood pressure and symptoms such as nervousness, headache, and uncontrollable shaking of a part of the body. Your doctor will probably decrease your dose gradually over 2 to days for the regular tablet and 3 to 7 days for the extended-release tablet.
What Are Clonidine Ir Oral Tablets
Clonidine IR oral tablet is a generic prescription medication. Its FDA-approved to treat hypertension in adults. IR stands for immediate release, which means the medication is released into the bloodstream right away.
Clonidine IR oral tablets may be used alone or with other drugs. Theyre typically used as an add-on treatment to help lower high blood pressure thats not well managed by other drugs.
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How Much Lower Is Blood Pressure When Lying Down
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What Are The Possible Side Effects Of Clonidine
Get emergency medical help if you have signs of an allergic reaction: hives difficult breathing swelling of your face, lips, tongue, or throat.
- severe chest pain, shortness of breath, irregular heartbeats
- a very slow heart rate or
- a light-headed feeling, like you might pass out.
Common side effects may include:
- drowsiness, dizziness
- constipation, loss of appetite or
- sleep problems , nightmares.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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How Much Does Clonidine Lower Blood Pressure
HomeHow Much Does Clonidine Lower Blood Pressure
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Search Methods For Identification Of Studies
Electronic searches
The Cochrane Hypertension Information Specialist will search the following databases from date of inception for published, unpublished, and ongoing studies:
The subject strategies for databases will be modelled on the search strategy designed for MEDLINE. Where appropriate, these will be combined with subject strategy adaptations of the sensitivity and precisionmaximising search strategy designed by Cochrane for identifying randomised controlled ). We will not apply a language restriction to the database searches.
Searching other resources
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What Should I Know About Storage And Disposal Of This Medication
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture .
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA’s Safe Disposal of Medicines website for more information if you do not have access to a take-back program.
It is important to keep all medication out of sight and reach of children as many containers are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location â one that is up and away and out of their sight and reach.
What Side Effects Are Possible With This Medication
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
- slow, fast or pounding heart beat
- symptoms of blockage of the large bowel
Stop taking the medication and seek immediate medical attention if any of the following occur:
- signs of a serious allergic reaction
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
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Clonidine Ir Oral Tablet Side Effects
Clonidine IR oral tablets can cause mild or serious side effects. The following lists contain some of the key side effects that may occur while taking this drug. These lists do not include all possible side effects.
For more information about the possible side effects of clonidine IR oral tablets, talk with your doctor or pharmacist. They can give you tips on how to deal with any side effects that may be concerning or bothersome.
Note: The Food and Drug Administration tracks side effects of drugs it has approved. If you would like to notify the FDA about a side effect youve had with clonidine IR oral tablets, you can do so through MedWatch.
Is Weight Gain A Side Effect Of Clonidine Ir Oral Tablets
Weight gain has been reported in some people taking clonidine IR oral tablets. But these people may also have been taking other blood pressure medications, so its not known if clonidine caused the weight gain.
If you have unexplained weight gain while taking clonidine, talk with your doctor. They can help determine the possible cause of the weight gain and what your next steps should be.
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What If I Miss A Dose
If you miss a dose of clonidine IR oral tablets, take it as soon as possible. But if its almost time for your next scheduled dose, skip the missed dose and just take your next dose as usual. Do not take extra doses to make up for missing doses. Doing so could raise your risk for side effects.
If you miss more than one dose of clonidine, talk with your doctor right away. If you go without this medication for too long, it can cause your blood pressure to increase rapidly. This can cause dangerous side effects. To read more about this, see the Clonidine IR oral tablet withdrawal and dependence section below.
To help make sure that you dont miss a dose, try using a medication reminder. This can include setting an alarm or timer on your phone or downloading a reminder app. A kitchen timer can work, too.