Does Low Testosterone Indicate Poor Health
In recent years, researchers have noticed general links between low testosterone and other medical conditions. One study showed that in 2,100 men over age 45, the odds of having low testosterone were:
Experts don’t suggest that low testosterone causes these conditions. In fact, it might be the other way around. That is, men with medical problems or who are in poor general health might then develop low testosterone.
Research into the relationship between low testosterone and several other health conditions is ongoing.
Testosterone And Erectile Dysfunction
Erectile dysfunction becomes more common as men age. Testosterone levels decline with age. Many men with ED blame their sagging performance on sagging hormone levels. But are they correct?
To find out, the Massachusetts Male Aging Study surveyed 625 randomly selected men between the ages of 40 and 70. Forty-one percent of the men had moderate to severe erectile dysfunction, but there was no link between ED and levels of total testosterone, bioavailable testosterone, and sex hormonebinding proteins.
Doctors in Australia approached the question from the other direction, by measuring testosterone levels in 1,455 men who were referred for evaluation of ED. Fewer than 6% of the men had low testosterone levels.
ED is much, much more likely to result from cardiovascular disease, diabetes, and medication side effects than from testosterone deficiency.
What Is Testosterone Replacement Therapy
TRT or androgen replacement therapy is a treatment that doctors give to males who have testosterone deficiency and are showing symptoms of hypogonadism.
Taking prescription testosterone helps restore the levels of this hormone in the blood, reversing the symptoms of low testosterone. People who take it may notice improvements in alertness, sexual function, energy, mood, and overall well-being.
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A Study Of The Effect Of Topical Testosterone Replacement Therapy On Blood Pressure In Adult Male Participants With Hypogonadism
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|Recruitment Status : Active, not recruitingFirst Posted : February 18, 2020Last Update Posted : May 24, 2021|
Hypogonadism is an endocrine disorder characterized by absent or deficient testosterone levels along with signs and symptoms of androgen deficiency, including delayed development or regression of sexual characteristics, impaired sexual function and sense of well-being, depressed mood, decreased muscle strength associated with loss of muscle mass and reduced bone mineral density. AndroGel 1.62% has demonstrated its ability to increase total testosterone levels in the blood by absorption of testosterone through the skin when applied topically. This study will evaluate the effect of AndroGel 1.62% on systolic blood pressure using ambulatory blood pressure monitoring in hypogonadal men who use testosterone replacement therapy.
Participants will receive daily topical gel doses of AndroGel 1.62% for approximately 16 weeks.
|Participants will receive AndroGel 1.62% once daily||Drug: AndroGel 1.62%|
Study Finds Testosterone Supplementation Raises Blood Pressure In Obese Rats
- American Physiological Society
- Boosting testosterone levels with hormone supplements may not be safe or appropriate for all men with low testosterone , according to new research.
Boosting testosterone levels with hormone supplements may not be safe or appropriate for all men with low testosterone , according to new research. Recent findings will be presented today at the American Physiological Society’s Cardiovascular, Renal and Metabolic Diseases: Sex-Specific Implications for Physiology conference in Knoxville, Tenn.
Low T — also called hypogonadism — occurs when the body does not produce enough of the male sex hormone testosterone. Hypogonadism can occur at any age. In adult males it can be caused by obesity, the use of certain medications and normal aging. Long-term testosterone supplementation normalizes hormone levels and has been found to reduce risk factors associated with heart disease, such as high cholesterol, insulin resistance and systemic inflammation.
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Risks Of Prescription Testosterone Therapy
Before we close our article, we would like to discuss the risks of prescription testosterone therapy in men. By that, we are referring to alternative treatment forms like injections, skin patches, and gels. No matter which one you choose, each has its own side effects.
For example, testosterone patches can make your skin itch. Additionally, muscular injections can create mood swings in males. And if you choose the testosterone gel, our word of advice is to avoid sharing it with others.
Prescription forms of testosterone therapy can result in increased urination and fluid retention, not to mention bigger acne problems.
It can also lead to breast enlargement and reproductive health issues in males. As a matter of fact, it can even worsen the impact of sleep apnea in elderly adults.
Are you thinking about trying out testosterone replacement therapy?
First of all, congratulations. This is a great solution if you are a man who constantly suffers from low levels of testosterone. Make sure that your doctor gives you a blood test to see if your testosterone levels are impacting your general health.
That doesnt mean that you can skip out on regular exercise and a healthy diet. Rather, its best to combine your testosterone replacement therapy with both for optimal results. Dont forget to schedule follow-up monitoring appointments either.
Side Effects Of Testosterone Therapy
Risks and side effects of testosterone therapy may be reasons not to have the treatment or be reasons to stop if you’ve started. Make sure to ask your doctor about them. They include breast enlargement, acne, and skin reactions related to the testosterone gels, patches, and injections.
If you can get by the risks and side effects of testosterone therapy, your doctor will still need to make sure you are safe on testosterone. Most men can tolerate treatment well, and many men do get benefits, but you need to keep watch, Gilbert said.
Monitoring and screening should include periodic blood tests to monitor your testosterone levels, digital rectal exams to check your prostate, testing your blood for prostate-specific antigen to check for prostate cancer, and blood tests to check your red blood cell level, called a hemoglobin and hematocrit.
Finally, even if you do everything right, testosterone just does not work for some men,” Harris said. “If you dont feel any better after a trial of testosterone therapy, thats another reason not to take it.
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Testosterone And The Heart
Forget clothes. In a very real sense, testosterone makes the man.
It is responsible for the deep voice, increased muscle mass, and strong bones that characterize the gender. It stimulates the production of red blood cells by the bone marrow. The hormone also has crucial, if incompletely understood, effects on male behavior: it contributes to aggressiveness, and it is essential for the libido, or sex drive, as well as for normal erections and sexual performance. Testosterone stimulates the growth of the genitals at puberty and is responsible for sperm production throughout adult life.
Although testosterone acts directly on many tissues, some of its least desirable effects don’t occur until it is converted into another male hormone, dihydrotestosterone . DHT acts on the skin, sometimes producing acne, and on the hair follicles, putting hair on the chest but often taking it off the scalp. Male-pattern baldness is one thing, but prostate disease quite another: DHT also stimulates the growth of prostate cells, producing normal growth in adolescence but contributing to benign prostatic hyperplasia and possibly even prostate cancer in many older men.
Benefits Of Testosterone Therapy For Blood Pressure
Testosterone is important for your body and your blood pressure. One of the functions of testosterone is its conversion into estrogen by the enzyme aromatase. Although too much estrogen conversion is not good for the body, the right amount will help protect the arteries.
When we look at the results of testosterone replacement and high blood pressure readings in adults, we often find that not only do BP levels decline, but the other issues associated with metabolic syndrome also improve. Weight gain is a significant problem because people who are heavier than normal often have higher blood pressure levels. Additionally, their LDL cholesterol and triglyceride levels are also high.
After starting testosterone therapy, and high blood pressure levels are checked, most people start to see a difference around the end of the third month of treatment.
You should discuss any concerns about blood pressure, low testosterone, and hormone levels in general with a qualified and experienced hormone replacement therapy specialist. The experts at Kingsberg Medical offer free, confidential consultations to men and women throughout the US. Local diagnostic testing laboratories and affordable treatment options are available.
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What Is The Treatment For Hypertension
At Low T Center, well put together a hypertension treatment plan for you based on your overall health and lifestyle. For some people, changes in their lifestyle are sufficient to reduce their blood pressure. This might include cutting back on salt consumption, exercising, losing weight and eating nutritiously. However, some people may need medication to keep their blood pressure under control. Well keep working with you to find the right solution that will keep your blood pressure at healthy levels.
We are happy to answer any questions you have about your health or high blood pressure. If you are suffering from symptoms that may be related to high blood pressure or if you simply havent had a medical check-up for a while, make an appointment with us online. We can check your blood pressure and do a comprehensive health assessment to identify any underlying conditions that may be causing unpleasant symptoms.
Blood Clots With Testosterone Replacement Therapy
The 3rd TRT side effect can include the risk of blood clots. Testosterone can synergistically work with a lipid called thromboxane, and may increase mens blood vessel constriction. What can happen is the blood slows thus making, in therapy more blood clots to occur. This Deep vein thrombosis can happen to clots that form in major arteries or veins, particularly with the legs. The clots formed, if they break away from the veins can travel freely within the body. If they end up in the lungs to create a pulmonary embolism, and within the brain, can cause a stroke.
A patient could prevent this a couple different ways. Every year about 900,000 Americans die of thrombosis, some of those as a TRT side effect. In many cases a blood thinner would be prescribed but there are more issues with taking those types of pharmaceuticals that we will cover later.
To help protect against these TRT side effects a patient could start vigorous exercise and get the blood circulating, that boost can reduce your risk by 22%. Also sitting too long can put you at risk so get up every half an hour and pace around. Increase your intake of Vitamin K, which has shown to be very beneficial by breaking down arterial plaque and increasing the flexibility of arteries.
At the Mas Clinic we are dedicated to optimal mens health. Sign up today to get on our TRT waitlist and avoid TRT side effects.
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Re: Testosterone Replacement Therapy And Elevated Blood Pressure
You make some good points, especially about the importance of working with knowledgeable specialists and that TRT needs to be part of a comprehensive diet and exercise program. When I first started TRT, the additional testosterone seemed to give me the energy I needed to exercise more, which in turn helped me to lose weight and feel better, etc. When the positive effects faded, I consulted an endocrinologist and we did try all the forms of TRT: injections, topical lotions and these new tablets that attach to your gums , in different amounts and different dosing regimens. Nothing seemed to help, and all forms seemed to cause fluid retention and elevated blood pressure readings. I am continuing a diet and exercise program, though I find it slow going without the boost that TRT provided for a short period. I was mostly wondering if anyone had a similar experience with the effects of TRT fading, possibly related to fluid retention and/or elevated blood pressure. It could be that for whatever reasons my body cannot tolerate extra testosterone and that Ill just have to live with my natural low level, trying to control my blood pressure through diet and exercise.
Women And Children Beware
The FDA has received reports of premature puberty and behavioral changes in children who have inadvertently come into contact with a man’s testosterone gel. The FDA advises women and children to avoid contact with application sites on the skin of men who use these gels. Men should wash their hands with soap and water after each application. They should also cover the application site with clothing after the gel dries, and then wash the area with soap and water before any skin-to-skin contact with another person.
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What Are The Risks Of Hypertension
You might associate high blood pressure with an increased risk of heart attack or stroke. These are two of the main risks of high blood pressure, but there are other risks as well. The dangers of hypertension if left untreated include damage to other organs, such as your kidneys, eyes and brain. For these reasons, it is important to keep an eye on your blood pressure and to seek treatment if it is too high.
A Cardiovascular Concern With Hormone Therapy
In men with low testosterone, testosterone therapy has improved LDL cholesterol, blood pressure, body mass index, insulin sensitivity, and exercise performance. However, a clinical trial of testosterone therapy conducted in older men with a high prevalence of cardiovascular disease was halted in 2009 because of a high rate of heart attacks and strokes.
Another study published in 2013 retrospectively studied male veterans with low testosterone who either received or did not receive testosterone therapy. That study found the hormones use was associated with greater risk of all-cause mortality, heart attack, and stroke.
Further, there are questions about the association between testosterone therapy and cardiovascular events like heart attack. While some studies have highlighted the connections between this therapy and chances of developing heart problems, others note that evidence is as yet scant and warrants more research. However, in studies of men who used anabolic steroids, researchers found an increase in heart disease, leading them to question whether testosterone therapy also raises the risk.
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Understanding Testosterone And Blood Pressure
Need a hand understanding the relationship between testosterone and blood pressure?
We can show you the way.
Since low levels of testosterone are connected to poor heart health, TRT therapy can possibly reverse these effects. By increasing the amount of testosterone in your body, you can widen arteries and reduce cardiovascular problems at the same time.
Still not convinced?
Consider this: While TRT therapy has limited side effects, there are a bunch of risks associated with other testosterone treatments. This includes symptoms such as increased urination, fluid retention, and acne problems.
In the end, the decision is easy. For those who want all of the benefits and less of the side effects, there is no better treatment than testosterone replacement therapy.
Interested in receiving testosterone replacement therapy?
If so, to schedule an appointment now!
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Testosterone Therapy And Cardiovascular Function
Low testosterone levels have been linked to various cardiac risk factors, but that doesn’t prove that low levels actually cause heart disease. Still, if testosterone therapy could help men with heart disease, it would bolster the argument that testosterone may be safe for the heart. Only a few small, short-term studies have been published to date, and the results offer mixed support for this theory.
Blood vessels and heart muscle cells have receptors that latch on to testosterone. Men who undergo androgen-deprivation therapy develop abnormally stiff arteries. In men with atherosclerosis and normal testosterone levels, short-term treatment with testosterone improves vascular reactivity and blood flow.
If testosterone helps blood vessels widen, it might be able to improve angina in men with coronary artery disease. A 2000 trial evaluated 46 men with stable angina and low-normal blood testosterone levels who were randomly assigned to 12 weeks of treatment with a testosterone patch or a placebo. Each man underwent a standard exercise stress test before and after treatment. Compared with the placebo-treated subjects, men on testosterone displayed improved exercise tolerance at the end of the trial but the difference was slight, amounting to an average gain of just 26 seconds.
Testosterone Therapy Increases The Risk Of Heart Disease
A growing body of research indicates that testosterone therapy is associated with an increased risk of cardiovascular disease in men. A study conducted by the National Institutes of Health followed 56,000 middle-aged and older men who were prescribed testosterone therapy between 2008 and 2010. It was found that men 65 years of age and older had a twofold increase in risk of heart attack within just 90 days of starting testosterone therapy. In addition, men younger than 65 years of age with a history of heart disease experienced a two- to threefold increased risk of heart attack when taking testosterone.
Another large study published in JAMA: TheJournal of the American Medical Association discovered that men with a history of heart disease had a 30 percent increase in mortality, heart attacks, and stroke after commencing testosterone therapy. Several systematic reviews of the medical literature regarding testosterone therapy have further backed up these findings, confirming that exogenous testosterone is strongly associated with an increased risk of cardiovascular events.
Risk-free ways to raise testosterone without replacement therapy #testosterone #hearthealth