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Angiotensin Receptor Blockers :
ARBs also block the renin angiotensin system , similar to ACEIs, but have a different mechanism of action by blocking the actions of angiotensin II in the tissues rather than the generation of angiotensin II, which is the action of ACEIs. These drugs also have an excellent acceptability and preservation of quality of life. Moreover, they do not cause an irritant cough or the rare danger of swelling of the lips, tongue and throat, that can occur with ACEIs. In general, the indications for their use, their effectiveness and beneficial interactions with thiazides and loop diuretics are similar to ACEIs. Some studies have suggested they are particularly effective in preventing stroke and that they may have an additional action to diminish the progression of Alzheimerâs disease in those with early dementia, but this requires conformation.
Individual Drugs ARBs include: candesartan , eprosartan , irbesartan , losartan , olmesartan , telmisartan and valsartan . As with ACEIs, there are only minor differences between agents in this class of drugs. All are effective in lowering blood pressure when given once, or perhaps twice daily.
Adverse Effects: As discussed, these drugs do not cause irritant cough, but otherwise have a similar spectrum of adverse actions to ACEIs.
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What Are The Symptoms Of High Blood Pressure
Most people experience no symptoms when their blood pressure is high. Sometimes people may develop a headache or feel unwell however, most do not connect these vague symptoms as having to do with their heart.
If high blood pressure is left untreated, it can damage the blood vessels and increase a persons risk of having a stroke or a heart attack. It also causes the heart to enlarge and weaken because it essentially wears itself out from having to work so hard to push blood around the body. People with high blood pressure are also more likely to develop high cholesterol, kidney and eye problems, and have poor circulation in the legs and feet.
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To determine the negotiation topics, you must first clarify what issues you want to raise and which issues you want all blood pressure medications to discuss.
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How Is High Blood Pressure Diagnosed
It is not uncommon for your blood pressure to go high occasionally however, it is persistently high blood pressure that is a concern. For this reason, if a doctor or nurse takes your blood pressure and it is high but you dont have any risk factors or symptoms, then at least two other separate measurements should be taken before you are diagnosed with high blood pressure.
Before getting your blood pressure taken you should avoid the following for at least an hour before the measurement:
- Strenuous exercise
- Stressful situations.
Sit down for at least five minutes before the reading is taken and dont talk while it is being measured.
Other tests may be ordered if your doctor concludes you have high blood pressure. These may include blood tests, an electrocardiogram, and sometimes a chest x-ray.
How Do Doctors Decide On The Best Blood Pressure Medication
When choosing from these classes, your doctor will consider many factors, including your other health conditions and your race.
For example, African American people seem to benefit most from starting treatment with a thiazide diuretic or a calcium channel blocker, studies suggest. However, someone with diabetes may benefit more from using an ACE inhibitor.
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Are Blood Pressure Medications Right For You
When youre first diagnosed with high blood pressure you might not need to take medications. Your doctor or nurse might suggest you make healthy changes to your lifestyle first, which could be enough to lower your blood pressure to a healthy level, but if thats not enough on its own, they may suggest you take medications as well.
The role of blood pressure medicines is to lower your risk of heart disease, stroke, and other health problems. So, whether you would benefit from them depends not only on your blood pressure, but on your overall health and risk of disease. Your doctor will consider a number of things, including:
- your age, ethnicity, family history and lifestyle
- any which raise your risk of heart attack or stroke, such as high cholesterol, being overweight, diabetes, kidney problems and diseases of the blood vessels such as coronary heart disease
- if members of your family have high blood pressure, strokes or heart attacks, or have done in the past
- any other illnesses you may have and medications youre taking, and any side effects
How high does your blood pressure need to be before starting medications?Your doctor will consider your when deciding whether to prescribe medications.
Your doctor will want to bring your blood pressure down to a target level, for example around 140/90mmHg.
What Is The First Drug Of Choice For Hypertension
First-line options include these blood pressure medication names: Thiazide diuretics, calcium channel blockers and for people who have kidney disease and heart failure angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers . Beta-blockers may also be first-line choices if you have a history of heart disease.
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How Long Is Medication Needed For
In most cases, medication is needed for life. However, in some people whose blood pressure has been well controlled for three years or more, medication may be able to be stopped. In particular, this may be possible for people who have made significant changes to lifestyle . Your doctor can advise you.
If you stop medication, you should have regular blood pressure checks. In some cases the blood pressure remains normal. However, in others it starts to rise again. If this happens, medication can then be started again.
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How Do Blood Pressure Medicines Work
Blood pressure medicines work in different ways to lower blood pressure:
- Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers keep your blood vessels from narrowing as much
- Calcium channel blockers prevent calcium from entering the muscle cells of your heart and blood vessels. This allows the blood vessels to relax.
- Diuretics remove extra water and sodium from your body. This lowers the amount of fluid in your blood. Diuretics are often used with other high blood pressure medicines, sometimes in one combined pill.
- Beta blockers help your heart beat slower and with less force. This means that your heart pumps less blood through your blood vessels. Beta blockers are typically used only as a backup option or if you also have certain other conditions.
Often, two or more medicines work better than one. While taking the medicines, it is still important to keep up with your healthy lifestyle changes.
NIH: National Heart, Lung, and Blood Institute
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Make Lifestyle Changes First
Even if you don’t have high blood pressure, it’s important to take steps to keep it under control because it tends to get higher with age. That’s especially important if you’re a black American or have a family history of the condition, since both sharply increase the risk of developing it. And a healthy diet and lifestyle are essential if you already have high-normal readings. For people with high blood pressure, lifestyle measures can sometimes reduce or even eliminate the need for drugs. For example, research has found that the DASH diet can be as effective as medication for some people with mild hypertension. This relatively low-sodium diet relies on fruit, vegetables, and low-fat dairy products. The potassium in those foods, and possibly the calcium, too, appear to help control blood pressure. For people with normal blood pressure and no heart disease or stroke risk factors, the suggested 2,400 mg daily sodium limit, achievable by adopting the DASH diet alone, might help ward off the upward creep of blood pressure that can occur with age. Other steps include losing excess weight, exercising regularly, and drinking alcohol only in moderation, as shown in the table below.
| Aim for a body mass index under 25. | 2.5 to 10 mmHg for about every 11 pounds |