Study Finds Painkillers Raise Blood Pressure
By Maggie Fox, Health, Science Editor
4 Min Read
WASHINGTON â Popular painkillers such as aspirin, ibuprofen and acetaminophen can raise blood pressure and thus the risk of heart disease among men, U.S. researchers reported on Monday.
Bayer Aspirin is seen in this undated file photo. Popular painkillers such as aspirin, ibuprofen and acetaminophen can raise blood pressure and thus the risk of heart disease among men, U.S. researchers reported on Monday. REUTERS/ File/PRNewsFoto
Men who took such drugs for most days in a week were about one-third more likely to be diagnosed with high blood pressure than men not taking them, the researchers found.
Their findings, published in the Archives of Internal Medicine, reinforce a study published in 2002 that these commonly used drugs raise blood pressure in women.
This is a potentially preventable cause of high blood pressure, Dr. John Forman of Brigham and Womens Hospital in Boston, who led the study, said in a statement.
Millions of people take the painkillers as pills every day to treat headaches, arthritis, muscle pulls and other aches and pains.
These are the three most commonly used drugs in the United States, Dr. Gary Curhan, who also worked on the study, said in a telephone interview.
Men who took acetaminophen , sold generically and under the Tylenol brand name, six or seven days a week were 34 percent more likely to be diagnosed with high blood pressure than men who did not take analgesics.
How Biotin Affects Test Results
Although supplementing with biotin can be beneficial for the body, this substance can greatly interfere with test results. The FDA mentioned that biotin could alter blood test results and cause incorrect diagnosis for certain health conditions.
It is recommended that you stop biotin supplementation at least 72 hours before offering a blood or saliva sample.
What Prescription Pain Medications Do Not Raise Blood Pressure
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Maximum Recommended Daily Dose
People should only use OTC naproxen for a short-term period of between 35 days for pain and no more than 3 days for fever. If they need ongoing treatment, people should consult their doctor first.
For children between 212 years old, the maximum daily dose by weight is 20 mg/kg. They should not be taking more than 1,000 mg in 24 hours.
When OTC medications, children 12 years and older should not take more than 660 mg in 24 hours.
Studies have not shown any benefit in using daily doses higher than 1,000 mg, but some sources suggest a maximum of
- blood clots
People with high blood pressure should only take naproxen cautiously.
Naproxen can cause sodium retention in the kidneys, which can result in increased blood pressure. A person with high blood pressure should consult their doctor before taking naproxen.
Gastrointestinal side effects of taking naproxen can be severe. Bleeding in the stomach, the formation of ulcers, and stomach or intestinal blockages can occur when taking naproxen. Most often, older adults are the most vulnerable age group for gastrointestinal side effects.
People who have a history of ulcers or gastrointestinal bleeding have a 10-fold higher risk for developing a bleed when taking naproxen. For these individuals, even short-term treatment can be risky.
Naproxen may interact with several prescription and nonprescription drugs. Drinking alcohol and taking naproxen may increase the risk of gastrointestinal side effects.
Reviewed by Michael Espelin APRN
Aleve Causes Gastrointestinal Problems
Aleve contains naproxen which is its active ingredient.
Use of Aleve drugs in patients may cause heartburn. Other serious gastrointestinal effects of Aleve drugs include peptic ulceration, allergic sialadenitis and eosinophilic colitis.
Peptic irritation may be asymptomatic.
It is advisable for the patient to undergo occasional monitoring of hematocrit levels.
Most people who are at the risk of gastrointestinal side effects are those who are alcoholic. Thereforre, Aleve drugs should be used with caution in alcoholic patients.
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Is There An Anti
Most NSAIDs can raise blood pressure to different degrees. That said, naproxen affects blood pressure less than ibuprofen. But it still shares other similar side effects with ibuprofen like kidney damage and stomach bleeding. Make sure to ask your pharmacist or healthcare provider if its OK for you to take any NSAIDs if you have high blood pressure.
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What About Topical Nsaids
A topical NSAID such as Voltaren Gel or Pennsaid Topical Solution might be one approach. This requires a conversation with a physician as such drugs are only available by prescription in the U.S. Our new guide discusses this option in great detail. Or perhaps this person would benefit from an anti-inflammatory herbal medicine such as boswellia or curcumin or a home remedy like tart cherry juice or Knox Gelatin.
You can learn about all these options in our newly revised and expanded Guide to Alternatives for Arthritis, available online at www.PeoplesPharmacy.com. This 53-page guide has links to scientific support for non drug approaches. We also provide videos so you can see exactly how to make recipes for arthritis remedies like gin-soaked raisins or Certo and grape juice. To make this brand new guide more affordable we have reduced the price. Act now to get Graedons Guide to Alternatives for Arthritis at an introductory discount.
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This Reader Wants To Know If Acetaminophen Will Raise Blood Pressure:
Q. I have taken NSAIDs for pain relief, but they bump up my blood pressure. When I had some dental work done, I took Advil for the throbbing pain. When I checked my blood pressure, it had spiked about 40 points over my usual number.
Is Tylenol less likely to be a problem? I try to avoid pain meds as much as possible, but occasionally I have to take something.
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How Can I Lower My Blood Pressure In Minutes
If your blood pressure is elevated and you want to see an immediate change, lie down and take deep breaths. This is how you lower your blood pressure within minutes, helping to slow your heart rate and decrease your blood pressure. When you feel stress, hormones are released that constrict your blood vessels.
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Risks And Side Effects Of Nsaids
The most common general side effects of NSAIDs are nausea, stomach upset and heartburn, according to the University of Wisconsin-Madison School of Medicine and Public Health . It’s important to note that you do not take it on an empty stomach, and you should not use NSAIDs for more than 10 days without speaking with your doctor.
UW Health notes that NSAIDs can also increase your risk of stroke, heart attack, internal bleeding and other health problems. People over age 65 and those with heart, liver, stomach, intestinal diseases or kidney diseases face greater risk of problems that may come with taking NSAIDs.
And if you’re pregnant or breastfeeding, you should consult with your doctor about whether you can take NSAIDs.
UW Health says you should also speak with your doctor if you want to take NSAIDs and have any of the following:
- Bleeding problems.
- Stomach pain or upsetstomach.
- Ulcers or a history ofintestinal or stomach bleeding.
- A habit of consumingmore than three alcoholic beverages per day, which can increase your risk ofstomach bleeding.
- Heart, kidney or liverdisease.
Acetaminophen Can Raise Hypertension Risks
I take six Tylenol Arthritis Pain pills every day. They contain 650 mg each of acetaminophen.
I read recently that acetaminophen can increase blood pressure. Should I worry?
You are taking the maximum allowable daily dose of acetaminophen .
Recent research has shown that rou tine use of as little as 500 mg of this pain reliever daily may elevate the risk of developing high blood pressure for some women.
The Nurses Health Study has been following thousands of women for decades. Those who relied on acetaminophen nearly doubled their likelihood of developing higher blood pressure within a three-year period .
Regular use of ibuprofen and naproxen also raised the risk of hypertension.
Another study found that regular use of acetaminophen might also increase the risk of kidney disease. And too much acetaminophen, especially when combined with alcohol, may put a strain on the liver.
If you read the label carefully you will find that you should not take this much acetaminophen for more than 10 days unless you are under medical supervision. Please discuss the new findings with your physician.
Is it beneficial to eat yogurt when taking antibiotics? Doctors dont seem to mention this when prescribing such drugs.
Many broad-spectrum antibiotics can upset the digestive tract by killing off good intestinal bacteria. Swallowing live yogurt cultures or probiotic supplements may re-establish proper balance.
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So Which Painkiller Is Best If You Have High Blood Pressure
If you have high blood pressure and a painful condition such as osteoarthritis, which requires regular non-steroidal anti-inflammatory painkiller, whatever you do, avoid taking ibuprofen. Talk to your doctor about whether or not another type of painkiller might suit you better.
Bear in mind that pain, in itself, can raise blood pressure, so it is important to find a safe way to control your symptoms. A topical pain-relieving cream or gel is worth trying, for example. The amount of diclofenac absorbed through the skin when using a Voltarol gel is a drop in the ocean compared to the amount absorbed into the circulation when taken by mouth. Having said that, read the Voltarol Emulgel Patient Information Leaflet within the pack carefully, as applying the gel to multiple sites is not recommended, and the area covered is usually just the zie from 1 penny to a 2 pence piece! If you overuse Voltarol Gel, your blood pressure could well go up so monitor it carefully. Paracetamol is also effective for some people, but not for others.
Whenever you start a new medicine its vitally important to monitor your blood pressure regularly to see if your hypertensive control changes.
If your blood pressure is raised, self-monitoring is key to maintaining good control.
Image credits: pixabay
What Happens When Ibuprofen Side Effects Include Hypertension
Many health professionals may not link a patients elevated blood pressure to their use of an NSAID. Yet ibuprofen side effects include hypertension, irregular heart rhythms , congestive heart failure, indigestion, perforated ulcers, kidney damage, kidney disease, liver damage and allergic reactions.
It would be a shame to start taking blood pressure medicine to counteract ibuprofen side effects. The person who asked the question at the top of the page may want to consider a different way to dealing with kneed pain.
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Higher Risk Of Serious Bleeding
Although ibuprofen isnt considered a blood thinner, it carries a risk of serious bleeding. This risk is usually low. But there are some people who should be more cautious when taking NSAIDs.
While ibuprofen has a low risk of liver damage, you should avoid it if you have liver cirrhosis . People with liver cirrhosis have a higher risk of bleeding when taking NSAIDs.
NSAIDs, like ibuprofen, also interfere with platelets abilities to stop bleeding. Platelets are a blood cell that help keep bleeding in check. So if you have a history of thrombocytopenia when you have low platelets in your blood ibuprofen may raise your risk of bleeding.
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What Is Advil Pm
Diphenhydramine is an antihistamine. Ibuprofenis a nonsteroidal anti-inflammatory drug .
Advil PM is a combination medicine used to treat occasional insomnia associated with minor aches and pains. Advil PM is not for use in treating sleeplessness without pain, or sleep problems that occur often.
Advil PM is for use in adults and children at least 12 years old.
Advil PM may also be used for purposes not listed in this medication guide.
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Do Ibuprofen Side Effects Include Scary High Blood Pressure
We have heard ibuprofen referred to as vitamin I. Thats because a lot of weekend warriors rely on ibuprofen and other non steroidal anti-inflammatory drugs to relieve inflammation and pain. Naproxen is also a favorite of hikers, golfers, bikers and tennis players. Many people with arthritis also rely on prescription-strength drugs like celecoxib, diclofenac and meloxicam. What many people do not realize is that ibuprofen side effects can be serious. Other NSAIDs pose similar risks.
Q. I was prescribed high-dose ibuprofen for a knee injury. Two months later, I went to a new primary doctor. My blood pressure was 188/100. It is normally 120/70. Does ibuprofen raise blood pressure?
A. Ibuprofen and other nonsteroidal anti-inflammatory drugs can in fact raise blood pressure .
Effects Of Nonsteroidal Antiinflammatory Drugs In Conventional Dosage On Glucose Homeostasis In Patients With Diabetes
Effects of nonsteroidal antiinflammatory drugs in conventional dosage on glucose homeostasis in patients with diabetes. Larger-than-conventional doses of nonsteroidal antiinflammatory drugs are known to lower plasma glucose levels. This phenomenon has raised thequestions whether or not NSAIDs in conventional dosage can be used for thetreatment of hyperglycemia in patients who have non-insulin-dependent diabetesmellitus and whether or not NSAIDs added to preexistent hypoglycemic drug therapytaken orally may lead to unanticipated hypoglycemia. In this study we evaluatedaspirin, sodium salicylate and ibuprofen given in conventional dosage tohyperglycemic patients with adult-onset diabetes. Half the patientswere usually treated for hyperglycemia by means of diet only and half with dietplus hypoglycemic drugs given orally. Significant changes in plasma glucoselevels were not seen after the administration of a combination drug containingaspirin and magnesium-aluminum hydroxide or sodium salicylate . Astatistically significant but small change was seen with the administration ofibuprofen but not when giving ibuprofen . The results of this study indicate thatconventional doses of NSAIDs should not be used for treating hyperglycemia andthat, since the additive hypoglycemic effect of NSAIDs in conventional doses was minimal or negligible, they can be used safely for other purposes in diabeticpatients taking hypoglycemic drugs orally.Continue reading > >
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Aspirin And Nonselective Nsaids
Two meta-analyses evaluated aspirin trials that included data on blood pressure.1,2 Aspirin dosages were greater than 1.5 g per day. There was no statistically significant effect on blood pressure. In a trial of 18,700 patients with hypertension, participants were randomized to receive aspirin or placebo for a mean of 3.8 years.3 There was no effect on blood pressure. There were significant reductions in rates of myocardial infarction among participants who were also receiving angiotensin-converting enzyme inhibitors .
A systematic review identified 32 randomized controlled trials that included 3,626 patients who were treated for at least four weeks with nonselective NSAIDs.4 Patients were monitored for changes in blood pressure and rates of hypertension during treatment. Most studies enrolled patients with osteoarthritis or rheumatoid arthritis, although some included patients with other conditions. Patients who received ibuprofen had a greater incidence of new hypertension compared with those in the control group .
This Is When To Be Cautious About Taking Ibuprofen
The American Society of Health-System Pharmacists recommends talking to your doctor before taking ibuprofen if you smoke, if you have high cholesterol or diabetes, or if you or anyone in your family has ever had heart disease, a heart attack, or a stroke. You’ll also want to talk to your doctor if you currently have high blood pressure , as ibuprofen can exacerbate the problem. You should immediately get emergency medical care if you develop chest pain, slurred speech, shortness of breath, or weakness in one part of the body. Furthermore, ASHP warns against taking ibuprofen immediately before or after coronary artery bypass graft surgery.
When you do take ibuprofen, you should check the bottle and take no more than the recommended amount. A 2018 study published in Pharmacoepidemiology & Drug Safety found that 11% of regular ibuprofen users take too much of the drug, putting themselves at risk of serious side effects.
If you decide against taking ibuprofen for the sake of your blood pressure, you may be happy to learn that aspirin does not share this side effect .
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