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How Does Kidney Disease Cause Hypertension

How Is Kidney Disease Treated

How diabetes and hypertension can lead to chronic kidney disease

For patients who have high blood pressure and kidney disease, the most important treatment is to control your blood pressure through lifestyle changes. ACE inhibitor and angiotensin II receptor blocker drugs lower blood pressure and can protect the kidneys from further damage, especially in people with diabetes. However,à treatments needà to be individualized.

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What Are The Kidneys And What Do They Do

Healthy kidneys filter about a half cup of blood every minute, removing wastes and extra water to make urine. The urine flows from each kidney to the bladder through a pair of thin tubes called ureters, one on each side of your bladder. Your bladder stores urine. Your kidneys, ureters, and bladder are part of your urinary tract system.

Is There A Causal Relationship

The researchers enrolled 3,749 residents of the town of Watari who had undergone an annual health check in 2017 and gathered information about their blood pressure levels and nocturia using questionnaires.

The data showed that getting up in the night to urinate was associated with a 40 percent greater chance of having high blood pressure, and the risk of hypertension rose significantly as the number of nocturia events per night increased.

Dr. Konno says that the results do not prove a causal relationship between nocturia and hypertension, and they may not apply to people who live outside Japan. The relationship may be influenced by various factors including lifestyle, salt intake, ethnicity, and genetic background, the researcher explains.

Hypertension is a national disease in Japan. The average salt intake in Japan is approximately 10 grams per day, which is more than double the average salt intake worldwide . This excessive salt intake is related to our preference for seafood and soy sauce-based food, so salt restriction is difficult to carry out, says Dr. Mutsuo Harada, the conferences press coordinator.

Dr. Harada adds that early detection and management of hypertension are crucial to prevent heart disease. It is important to research and understand the cause of nocturia in patients because this disorder can not only result from urinary organ problems it may also be caused by diseases such as hypertension.

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Protein Or Blood In The Urine

Urinalysis or urine testing is used to look for abnormalities such as an excess amount of protein, blood, pus, bacteria or sugar. A urine test can help to detect a variety of kidney and urinary tract disorders, including chronic kidney disease, diabetes, bladder infections and kidney stones. A trace of one type of protein, albumin in urine is an early sign of chronic kidney disease. Persistent amounts of albumin and other proteins in the urine indicate kidney damage. The presence of albumin is also a risk factor for cardiovascular events and death.

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Relationship Between Renal Histological Analysis And Clinical Characteristics

Hypertensive Renal Disease. Causes, symptoms, treatment Hypertensive ...

Tables 3 and 4 show the relationship between renal histological analysis and clinical characteristics. SG was significantly correlated with smoking , estimated glomerular filtration rate , urinary protein , ABPHT , CBPHT , NT , and SHT . IF was significantly correlated with smoking , eGFR , urinary protein , ABPHT , CBPHT , NT , and SHT . As for intra-renal vascular lesions, ILA was significantly correlated with age and eGFR . AH was significantly correlated with age , male sex , smoking , total cholesterol , ABPHT , CBPHT , NT , MHT , and SHT . In the multivariate analysis, SG and IF were significantly correlated with eGFR and urinary protein. ILA was significantly correlated only with age, whereas AH was significantly correlated with age and ABPHT.

Table 3

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Reducing Albuminuria: A Biomeasure Of Central Aortic Pulse Pressure

Could a therapeutic intervention, predict benefit with regard to kidney disease progression and even risk for subsequent cardiovascular events? Could the glomeruli within the kidneys serve as a barometer of an appropriate BP goal in an individual patient? This latter issue would be of substantial importance in patients with impaired renal autoregulation due to afferent arteriolar injury, which would result in an increase in glomerular capillary hydraulic pressure in direct proportion to systemic BP. Because the renal arteries directly come off of the central aorta, specific measures of central aortic pulse pressure by response to treatment may be of value in predicting the anti-proteinuric response and vice versa. A careful analysis of available clinical trial data suggests that this may indeed be the case. As will subsequently be discussed, a lower level of brachial artery BP sufficient to reduce glomerular capillary pressure is necessary. Current guidelines suggest that microalbuminuric patients have a goal BP below 130/80 mmHg .

Traditionally, we have used brachial artery cuff BP measurements to determine adequacy of therapy. However, some analyses suggest that changes in proteinuria may be more predictive of renal disease progression in nephropathic diabetics compared with brachial artery cuff BP measurements . Why? Is this simply a poor technique for measuring BP?

How Renal Disease Cause Hypertension

But a small number of high blood pressure patients have secondary hypertension, which means an underlying disease is identified as the cause. During.

high blood pressure over time, this can put strain on the small blood vessels in the kidneys and stop the kidneys working properly diabetes too much.

Age-related Associations of Hypertension and Diabetes Mellitus with Chronic Kidney Disease Background: Studies suggest end-stage renal disease incidence and all-cause mortality rates among.

The association of diabetes mellitus and hypertension with CKD across the adult lifespan.

Number of adults aged 18 and over with diagnosed kidney disease: 6.0 million Percent of adults aged 18 and over with diagnosed kidney disease: 2.4% Source: Summary Health Statistics Tables for U.S. Adults: National Health Interview Survey,

Uncontrolled high blood pressure is one of the leading causes of chronic kidney disease and kidney failure in the United States. · High blood pressure can damage.

The evidence that moderate hypertension is an important primary cause of renal failure is.

Obesity is potent factor for the development of major risks for chronic kidney disease, like diabetes and hypertension, and.

The chances of CKD being prevented, detecting earlier or cured are higher when a reliable and appropriate healthcare service.

High blood pressure, also called hypertension, is a leading cause of kidney disease and kidney failure .

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How Is Renal Hypertension Diagnosed

It is important to see your healthcare provider regularly to make sure your blood pressure numbers are checked and are within the normal range. He or she may recommend blood tests.

A healthcare provider can gather clues that vascular disease may be present by taking a thorough history and performing a physical exam. If you have a history of other vascular diseases, such as heart attacks or strokes, you are at higher risk for having renal artery stenosis. One exam, listening to the neck or belly with a stethoscope, may help identify narrowed arteries. When blood flows through a narrowed artery, it sometimes makes a whooshing sound, called a bruit.

Healthcare providers may order one of the imaging tests below to look for narrowed kidney arteries. However, finding a narrowed kidney artery alone does not mean that your high blood pressure is due to renal hypertension. Many people have narrowing of kidney arteries without high blood pressure or with high blood pressure that is not caused by the narrowing . The healthcare provider will need to use other clinical clues to help determine if the two are connected.

Imaging tests that can be done to see if the kidneys arteries have narrowed include:

Are There Special Medications For Hypertension If You Have Kidney Disease

How does diabetes cause kidney disease?

Two types of medications can help lower blood pressure and slow the progression of kidney disease: ACE inhibitors and ARBs.

  • ACE inhibitors help to prevent the body from producing as much angiotensin. This helps the blood vessels to relax.
  • ARBs keep angiotensin from binding with receptors. This can also help the blood vessels to relax. This is key to slowing the progression of kidney disease.

In addition to these medications, your healthcare professional may prescribe a diuretic to help the kidneys remove excess sodium and fluid from the body.

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What Can I Do To Help Control My High Blood Pressure

A healthy lifestyle is key to helping control any type of hypertension. Making changes in daily habits can help, such as:

  • Eating a heart-healthy diet: Choose fruits, vegetables, grains and low-fat dairy foods.
  • Exercising regularly, at least 30 minutes a day of moderate activity, such as walking .
  • Keeping your weight under control: Check with your healthcare provider for a weight-loss program, if needed.
  • Quitting smoking, if you smoke.
  • Cutting back on alcoholic drinks.
  • Limiting caffeine intake.
  • Limiting sodium in your diet: Read nutrition labels on packaged foods to learn how much sodium is in one serving.
  • Reducing and avoiding stress when possible: Many people find that regular meditation or yoga helps.

How Do Doctors Treat High Blood Pressure

First, your doctor may suggest some healthy life changes. This may include:

  • Following a low-sodium eating plan
  • Being active for at least 30 minutes most days of the week
  • Quitting smoking or using tobacco
  • Drinking less alcohol

If healthy life changes are not enough to control your blood pressure, your doctor may give you a prescription blood pressure medicine. There are two types of blood pressure medicines that can also help protect your kidneys and slow down kidney disease:

  • ACE inhibitors : A group of medicines that lower blood pressure by widening your blood vessels, helping your kidneys get rid of extra water and lowering the levels of hormones that raise blood pressure
  • ARBs :A group of medicines that lower blood pressure by widening your blood vessels

Your doctor might also ask you to take a diuretic, also called a water pill. This helps your body get rid of extra fluid which can cause high blood pressure.

Be sure to take all medicines the way your doctor tells you to. Blood pressure medicines work best when you take them every day even if you feel fine.

Talk to your doctor if you have any side effects from your medicines. You may be able to take a different medicine that does not have those side effects.

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How Is Kidney Disease Diagnosed

As with high blood pressure, you may not realize that you have kidney disease. Certain laboratory tests can indicate whether your kidneys are eliminating waste products properly. These tests include serum creatinine and blood urea nitrogen elevated levels of either can indicate kidney damage. Proteinuria, an excess of protein in the urine, is also a sign of kidney disease.

Surgical Treatments For Renal High Blood Pressure

Why does chronic kidney disease cause hypertension?

If you cant control your disease with medication, in rare cases your doctor may suggest one of two surgeries:

  • Renal stenting. In this surgery, doctors widen the kidneys veins and insert a stent. This small metal tube helps keep blood flowing to the kidneys, even when high blood pressure has damaged the arteries.
  • Renal bypass. Surgeons first harvest a vein from elsewhere in your body. They then graft the vein into place so that it improves blood flow to the kidneys.

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How Can I Prevent Or Slow The Progression Of Kidney Disease From High Blood Pressure

The best way to slow or prevent kidney disease from high blood pressure is to take steps to lower your blood pressure. These steps include a combination of medicines and lifestyle changes, such as

  • being physically active
  • managing stress
  • following a healthy diet, including less sodium intake

No matter what the cause of your kidney disease, high blood pressure can make your kidneys worse. If you have kidney disease, you should talk with your health care professional about your individual blood pressure goals and how often you should have your blood pressure checked.

Diagnosis Of Kidney Disease

Early diagnosis and optimal management can often prevent kidney damage from becoming worse and reduce the risk of kidney failure.

Chronic kidney disease often has very few symptoms, or only general symptoms, such as tiredness, headaches and feeling sick. The doctor may begin by reviewing your medical history and performing a physical examination.

The diagnostic tests for kidney disease chosen by your doctor depend on factors including your symptoms, age, medical history, lifestyle and general health. Tests for kidney disease include:

  • urine tests

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What Are The Symptoms Of An Acute Kidney Infection

Signs and symptoms vary with age:

  • Newborns: no fever but poor feeding and vomiting
  • Children < 2: may have a fever , a poor appetite, vomiting and diarrhea
  • Children > 2: fever, appetite changes, stomach or lower back pain, symptoms of urgency, frequency and pain with urination

If a toilet trained child is having accidents during the day or night, it may be a sign of an infection. Typically a childs urine will have a strong, foul odor, and there may be blood in the urine.

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How Often Should I See My Doctor

Chronic kidney disease – causes, symptoms, diagnosis, treatment, pathology
  • Your CKD team will outline a treatment plan for you after you are diagnosed. Most patients come to the clinic 1 or 2 times per year. Well ask you to come in more often if:

  • You start a new medicine or we change your medicine dose.

  • Your kidney function is getting worse.

  • Your blood pressure is not controlled.

  • At each visit, we will test your blood and urine and measure your blood pressure.

  • DONT be afraid to ask questions. We are here to help you.

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    What Are Clinical Trials For High Blood Pressure And Kidney Disease

    Clinical trialsand other types of clinical studiesare part of medical research and involve people like you. When you volunteer to take part in a clinical study, you help doctors and researchers learn more about disease and improve health care for people in the future.

    Researchers are studying many aspects of high blood pressure and kidney disease, such as

    • managing high blood pressure through diet, education, and counseling in patients with kidney disease
    • testing new medications to treat high blood pressure and kidney disease

    Find out if clinical studies are right for you.

    How Polycystic Kidney Disease Causes Hypertension

    Kidney biopsy is a procedure that involves taking a small piece of kidney tissue for examination with a microscope. Biopsy results show the cause of the kidney disease and extent of damage to the kidneys. How is kidney disease in children treated? Treatment for kidney disease in children depends on the cause of the illness.

    Congenital cystic disease Usually diagnosed prenatally with sonograms before symptoms are present. Autosomal dominant polycystic kidney disease Chronic flank pain and/or intermittent blood in the urine . Some may have cyst hemorrhage, kidney infections, or kidney stones. Those in their 50s often develop hypertension and chronic.

    Disease progression occurs slowly over a period of time. It is caused due to polynephritis or polycystic kidney.

    Impaired kidney function can cause problems in all parts of the body.

    Pregnant women with polycystic.

    factor for heart disease for women over 40 Women with PCOS are at an increased risk for obesity, dyslipidemia, diabetes and high blood pressure Poly-Cystic.

    Several factors can put you at risk of getting kidney disease, such as high blood pressure, diabetes.

    One such disease is polycystic kidney disease . A genetic disorder, PKD causes.

    In a new study in Cell Stem Cell, scientists from the USC laboratory of Andy McMahon generated simple kidney.

    disease is a progressive neurodegenerative disorder and the most common cause.

    Medical news and health news headlines posted throughout the day, every day

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    How Does High Blood Pressure Affect The Kidneys

    High blood pressure can constrict and narrow the blood vessels, which eventually damages and weakens them throughout the body, including in the kidneys. The narrowing reduces blood flow.

    If your kidneys blood vessels are damaged, they may no longer work properly. When this happens, the kidneys are not able to remove all wastes and extra fluid from your body. Extra fluid in the blood vessels can raise your blood pressure even more, creating a dangerous cycle, and cause more damage leading to kidney failure.

    Causes Of Renal Hypertension

    What are three possible causes of hypertension?

    Renal hypertension is caused by a narrowing in the arteries that deliver blood to the kidney. One or both kidneys‘ arteries may be narrowed. This is a condition called renal artery stenosis.

    When the kidneys receive low blood flow, they act as if the low flow is due to dehydration. So they respond by releasing hormones that stimulate the body to retain sodium and water. Blood vessels fill with additional fluid, and blood pressure goes up.

    The narrowing in one or both renal arteries is most often caused by atherosclerosis, or hardening of the arteries. This is the same process that leads to many heart attacks and strokes. A less common cause of the narrowing is fibromuscular dysplasia. This is a condition in which the structure of the renal arteries develops abnormally for unclear reasons.

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    Can Kidney Infection Be Prevented

    Hygiene: The main approach to the prevention of kidney infection is proper hygiene. Because the majority of infections tend to happen due to the presence of bacteria entering the urinary tract from the urethra, proper personal hygiene plays theoretical importance in preventing urinary infections. For example, in women, wiping the genital area from front to back after going to the bathroom may significantly prevent bacteria around the anus or vagina to gain access to the urethra. Hygienic use of bathtubs and douching may also have a preventive role, but is not universally supported by clinical experts.

    Sex: Because sexual intercourse is another risk factor for kidney infection, it is advised to empty the bladder after sexual activity to drain bacteria that may have entered the bladder. This practice, however, is not overwhelmingly proven by available clinical data and not recommended by some experts.

    Antibiotics: Preventive antibiotic therapy can sometimes be helpful in women who have recurrent UTIs . This could be guided by the presence of symptoms suggestive of an infection or after sexual intercourse if infections are temporally associated with sexual intercourse. Preventive antibiotics are also recommended for patients undergoing invasive urologic procedures when bacteria are detected in screening urine culture.


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